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Science of Hypnosis Over and over, we hear the question, what is hypnosis and what is the science in it? A brain signature of being hypnotized was first seen in 2012 through functional MRI (fMRI), a kind of MRI showing brain activity with respect to changes in blood flow. Parts of the brain connected with executive control and attention were proven to have a role. In particular, hypnotized subjects exhibited stronger co-activation between components of the executive-control network (manages basic cognitive functions) and the salience network (decides which stimuli should receive attention). In their brains, both networks were activated simultaneously. In those who were not hypnotized, no such connectivity was seen. What drove these experiments to a higher plane is that researcher used fMRI to see which parts of brain get triggered as hypnotized subjects analyzed colors. The color sections in both left and right hemispheres were stimulated when the subjects were made to perceive colors. The researchers agreed that hypnosis is indeed a one-of-a-kind psychological state and definitely doesn’t come from adopting a role.
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Another exciting observation from these trials were the hemispheric variances between the hypnotized and non-hypnotized brain. When non-hypnotized subjects were instructed to perceive colors on a greyscale photograph, only right hemisphere was triggered. The left hemisphere, where reason and logic is processed, responded only during hypnosis.
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Another research used positron-emission tomography (PET) to look into cerebral blood flow in hypnotized subjects. The hypnotic state was related to activation of a number of mainly left-sided cortical sections and some right-sided areas. The trend of activation shared a lot of similarities with mental imagery, from which it showed differences by the relative deactivation of the precuneus (handles visuo-spatial imagery, episodic memory retrieval and self-processing operations of the brain). The trend of activation had plenty of similarities with mental imagery, from which it proved different by the relative deactivation of the precuneus, the part of the brain that takes care of the brain’s visuo-spatial imagery, episodic memory retrieval and self-processing operations. Some scientists believe that under hypnosis, the subjects simply activate, to a significant extent, the brain sections used in imagination, but without actual perceptual changes. Another functional MRI study displayed minimized activity in both anterior cingulate cortex (affects emotions, memory and learning) and visual areas during hypnosis. The outcome suggests that hypnosis has an influence on cognitive control by controlling activity in certain brain areas. In multiple studies, hypnotizable subjects exhibited substantially more brain activity in the emotion and behavior-affecting anterior cingulate gyrus, as compared to participants who are non-hypnotized. The anterior cingulate gyrus responds to mistakes and gauges emotional outcomes. Prefrontal cortex is related to with higher level cognitive processing and behavior. Comparison of findings from multiple studies also indicates quite contradictory results. Many regions of the brain seem to respond in different experiments. This can be related to various experimental techniques, both in terms of hypnotic approach and equipment used for the studies.